Conditional ISI Title Important Safety Information Important Safety Information

Conditional Full ISI Body: Before starting COSENTYX, tell your doctor if you:<ul><li>are being treated for an infection</li><li>have an infection that does not go away or that keeps coming back</li><li>have TB or have been in close contact with someone with TB</li><li>think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarhea or stomach pain; burning when you urinate or urinate more often than normal</li></ul>After starting COSENTYX, call your doctor right away if you have any signs of infection

Conditional Indication Full: INDICATION BODY ISI drawer is displayed open on desktop (closed on mobile) and is collapsible via the X in the upper right hand cornerWhat happens if I add a second paragraphBefore starting COSENTYX, tell your doctor if you:<ol class="primary_02-c"><li>are being treated for an infection</li><li>have an infection that does not go away or that keeps coming back</li><li>have TB or have been in close contact with someone with TB</li><li>think you have an infection or have symptoms of an infection&nbsp;such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal</li></ol>*After starting COSENTYX, call your doctor right away if you have any signs of infection listed above.*&nbsp;Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

Conditional Indication Information INDICATION TITLE How it works

<strong style="-webkit-text-stroke-width:0px;caret-color:rgb(23, 43, 77);color:rgb(23, 43, 77);font-family:-apple-system, BlinkMacSystemFont, &quot;Segoe UI&quot;, Roboto, Oxygen, Ubuntu, &quot;Fira Sans&quot;, &quot;Droid Sans&quot;, &quot;Helvetica Neue&quot;, sans-serif;font-size:14px;font-style:normal;font-variant-caps:normal;letter-spacing:-0.07px;orphans:auto;text-align:start;text-decoration:none;text-indent:0px;text-transform:none;white-space:pre-wrap;widows:auto;word-spacing:0px;" data-renderer-mark="true">&nbsp;Conditional <strong style="-webkit-text-stroke-width:0px;caret-color:rgb(23, 43, 77);color:rgb(23, 43, 77);font-family:-apple-system, BlinkMacSystemFont, &quot;Segoe UI&quot;, Roboto, Oxygen, Ubuntu, &quot;Fira Sans&quot;, &quot;Droid Sans&quot;, &quot;Helvetica Neue&quot;, sans-serif;font-size:14px;font-style:normal;font-variant-caps:normal;letter-spacing:-0.07px;orphans:auto;text-align:start;text-decoration:none;text-indent:0px;text-transform:none;white-space:pre-wrap;widows:auto;word-spacing:0px;" data-renderer-mark="true">Short ISI Body <a href="https://www.cosentyx.com">COSENTYX</a> is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:InfectionsCOSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections, sometimes serious.<ul><li>Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.</li><li>If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.</li><li>Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX.&nbsp;*Do not take COSENTYX if you have an active TB infection.*</li></ul>

1Conditional2 INDICATION Short BODY ISI drawer is displayed open on desktop (closed on mobile) and is collapsible via the X in the upper right hand cornerBefore starting COSENTYX, tell your doctor if you:<ol class="accent_03-c"><li>are being <a href="https://usim.bestage.usimtestblueprint.com/taxonomy/term/676/edit?destination=/admin/content/custom-isi">treated</a> for an infection</li><li>have an infection that does not go away or that keeps coming back</li><li>have TB or have been in close contact with someone with TB</li></ol>

<span class="primary_01-c" style="-webkit-text-stroke-width:0px;background-color:rgba(162, 166, 174, 0.08);color:rgb(23, 43, 77);display:inline !important;float:none;font-family:-apple-system, &quot;system-ui&quot;, &quot;Segoe UI&quot;, Roboto, Oxygen, Ubuntu, &quot;Fira Sans&quot;, &quot;Droid Sans&quot;, &quot;Helvetica Neue&quot;, sans-serif;font-size:14px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:-0.07px;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:pre-wrap;widows:2;word-spacing:0px;">ISI Title Important Safety Information&nbsp;

Before starting COSENTYX, tell your doctor if you:<ul class="ul1"><li class="li2">are being treated for an infection</li><li class="li2">have an infection that does not go away or that keeps coming back</li><li class="li2">have TB or have been in close contact with someone with TB</li><li class="li2">think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarhea or stomach pain; burning when you urinate or urinate more often than normal</li></ul>After starting COSENTYX, call your doctor right away if you have any signs of infection

INDICATION BODY ISI drawer is displayed open on desktop (closed on mobile) and is collapsible via the X in the upper right hand cornerWhat happens if I add a second paragraphBefore starting COSENTYX, tell your doctor if you:<ul class="ul1"><li class="li1">are being treated for an infection</li><li class="li1">have an infection that does not go away or that keeps coming back</li><li class="li1">have TB or have been in close contact with someone with TB</li><li class="li1">think you have an infection or have symptoms of an infection&nbsp;such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal</li></ul>After starting COSENTYX, call your doctor right away if you have any signs of infection listed above.&nbsp;Do not use COSENTYX if you have any signs of infection unless you are instructed to by your doctor.

<span class="primary_01-c" style="-webkit-text-stroke-width:0px;background-color:rgba(162, 166, 174, 0.08);color:rgb(23, 43, 77);display:inline !important;float:none;font-family:-apple-system, &quot;system-ui&quot;, &quot;Segoe UI&quot;, Roboto, Oxygen, Ubuntu, &quot;Fira Sans&quot;, &quot;Droid Sans&quot;, &quot;Helvetica Neue&quot;, sans-serif;font-size:14px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:-0.07px;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:pre-wrap;widows:2;word-spacing:0px;">INDICATION TITLE How it works

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:InfectionsCOSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections, sometimes serious.<ul class="ul1"><li class="li2">Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.</li><li class="li2">If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.</li><li class="li2">&nbsp;Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX.&nbsp;Do not take COSENTYX if you have an active TB infection.</li></ul>

INDICATION BODY ISI drawer is displayed open on desktop (closed on mobile) and is collapsible via the X in the upper right hand cornerBefore starting COSENTYX, tell your doctor if you:<ul class="ul1"><li class="li1">are being treated for an infection</li><li class="li1">have an infection that does not go away or that keeps coming back</li><li class="li1">have TB or have been in close contact with someone with TB</li></ul>

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