<span class="primary_01-c" style="-webkit-text-stroke-width:0px;background-color:rgba(162, 166, 174, 0.08);color:rgb(23, 43, 77);display:inline !important;float:none;font-family:-apple-system, &quot;system-ui&quot;, &quot;Segoe UI&quot;, Roboto, Oxygen, Ubuntu, &quot;Fira Sans&quot;, &quot;Droid Sans&quot;, &quot;Helvetica Neue&quot;, sans-serif;font-size:14px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:-0.07px;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:pre-wrap;widows:2;word-spacing:0px;">ISI Title Important Safety Information&nbsp; PI modal-Freeform <a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a> <a href="https://www.gmail.pdf/#pi-modal">https://www.gmail.pdf#pi-modal</a> <a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/n</a>

Before starting COSENTYX, tell your doctor if you:<ul class="ul1"><li class="li1">are being treated for an infection</li><li class="li1">have an infection that does not go away or that keeps coming back</li><li class="li1">have TB or have been in close contact with someone with TB</li><li class="li1">think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarhea or stomach pain; burning when you urinate or urinate more often than normal</li></ul>After starting COSENTYX, call your doctor right away if you have any signs of infectionPI modal-Freeform<a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.pdf/#pi-modal">https://www.gmail.pdf#pi-modal</a><a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.com/#pi-modal">https://www.gmail.com#pi-modal-External link</a><a href="https://www.google.com/#pi-modal">google.com-whitelist</a><a href="https://www.cosentyxhcp.com.pdf/#pi-modal">Allow list-cosentyxhcp</a>

<span style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(35, 36, 41);display:inline !important;float:none;font-family:&quot;system-ui&quot;, -apple-system, &quot;Segoe UI&quot;, Roboto, Oxygen-Sans, Ubuntu, Cantarell, &quot;Helvetica Neue&quot;, sans-serif;font-size:14.224px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;letter-spacing:normal;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Indication body fullPI modal-Freeform<a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.pdf/#pi-modal">https://www.gmail.pdf#pi-modal</a><a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.com/#pi-modal">https://www.gmail.com#pi-modal-External link</a><a href="https://www.google.com/#pi-modal">google.com-whitelist</a><a href="https://www.cosentyxhcp.com.pdf/#pi-modal">Allow list-cosentyxhcp</a>

<span style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(35, 36, 41);display:inline !important;float:none;font-family:&quot;system-ui&quot;, -apple-system, &quot;Segoe UI&quot;, Roboto, Oxygen-Sans, Ubuntu, Cantarell, &quot;Helvetica Neue&quot;, sans-serif;font-size:14.224px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;letter-spacing:normal;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Indication Title PI modal-Freeform <a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a> <a href="https://www.gmail.pdf/#pi-modal">https://www.gmail.pdf#pi-modal</a> <a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosen</a>

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having serious side effects such as:InfectionsCOSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections, sometimes serious.<ul class="ul1"><li class="li1">Your doctor should check you for tuberculosis (TB) before starting treatment with COSENTYX.</li><li class="li1">If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with COSENTYX and during treatment with COSENTYX.</li></ul>• •&nbsp; &nbsp;Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX.&nbsp;Do not take COSENTYX if you have an active TB infection.PI modal-Freeform<a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.pdf/#pi-modal">https://www.gmail.pdf#pi-modal</a><a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.com/#pi-modal">https://www.gmail.com#pi-modal-External link</a><a href="https://www.google.com/#pi-modal">google.com-whitelist</a><a href="https://www.cosentyxhcp.com.pdf/#pi-modal">Allow list-cosentyxhcp</a>

<span style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(35, 36, 41);display:inline !important;float:none;font-family:&quot;system-ui&quot;, -apple-system, &quot;Segoe UI&quot;, Roboto, Oxygen-Sans, Ubuntu, Cantarell, &quot;Helvetica Neue&quot;, sans-serif;font-size:14.224px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;letter-spacing:normal;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Indication body shortPI modal-Freeform<a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.pdf/#pi-modal">https://www.gmail.pdf#pi-modal</a><a href="https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal">https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf#pi-modal</a><a href="https://www.gmail.com/#pi-modal">https://www.gmail.com#pi-modal-External link</a><a href="https://www.google.com/#pi-modal">google.com-whitelist</a><a href="https://www.cosentyxhcp.com.pdf/#pi-modal">Allow list-cosentyxhcp</a>

Prescribing Information (PI)

Success is not merely the result of talent or luck, but a consistent commitment to hard work, resilience, and a positive mindset. Each challenge faced is an opportunity to grow, learn, and improve. While setbacks may momentarily discourage, they also provide valuable lessons that shape future achievements. Staying focused on long-term goals, maintaining discipline, and embracing change are key ingredients in any journey toward fulfillment. True success lies in the progress we make and the impact we leave on others along the way. Success is not merely the result of talent or luck.&nbsp; 123 12333310976

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